Bivalirudin Injection


Bivalirudin Injection

Specifications

Dosage 250mg
Usage Clinical, hospital etc.
Storage Cool and Dry Place
Form Liquid
Grade Standard Medicine Grade
Packaging Type Glass Bottle

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Description : Bivalirudin  is a specific and reversible direct thrombin inhibitor (DTI). It is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech Hirudo medicinalis).Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin.It inhibits both circulating and clot-bound thrombin.It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.

Additional Information : Bivalirudin is intended for IV use only and is supplied as a sterile, lyophilized product in single-use, glass vials. After reconstitution, each vial delivers 250 mg of bivalirudin.

Side Effects :

  • Very common - More than 1 in 10 people who have Bivalirudin
    • Minor bleeding from various sites of the body
  • Common -  More than 1 in 100 people who have Bivalirudin
    • Abnormal laboratory test results
    • Bruising
    • Injection site problems such as bleeding, pain, discomfort or collection of blood under the skin
    • Major bleeding from various sites of the body – certain types of bleeding may be fatal. Seek medical advice if you develop any Unusual bleeding
    • Thrombosis – this may be fatal
  • Uncommon - More than 1 in 1000 people who have Bivalirudin
    • Blood and bone marrow problems
    • Blood in the urine
    • Collection of blood under the skin
    • Coughing blood
    • Headaches
    • Hypersensitivity reactions such as tightness of chest, wheezing, anaphylaxis or anaphylactic shock. Anaphylaxis or anaphylactic Shock may be fatal
    • Lowered blood pressure
    • Melaena
    • Nausea
    • Nose bleed
    • Vomiting blood
  • Rare - More than 1 in 10,000 people who have Bivalirudin
    • Back pain
    • Breathing difficulties
    • Chest pain
    • Circulation problems
    • Fistula
    • Groin pain
    • Irregular heart rate
    • Other heart problems or a heart attack
    • Skin rash or rashes
    • Urticaria
    • Vomiting
  • Very rare - Fewer than 1 in 10,000 people who have Bivalirudin compartment syndrome

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